ESPU Congress 2018 - Abstract Book

128 29 th CONGRESS OF THE ESPU S16: RENAL TRANSPLANTATION Moderators: Wouter Feitz (Netherlands), Simona Gerocarni-Nappo (Italy) ESPU Meeting on Friday 13, April 2018, 13:30–13:54 13:30–13:33 S16-1 (PP) LONG-TERM OUTCOME OF PEDIATRIC RENAL TRANSPLANT IN BOYS WITH POSTERIOR URETHRAL VALVES (PUV) Doris HEBENSTREIT  1 , Alexander SPRINGER  2 , Karin HEBENSTREIT  3 , Dagmar CSAICSICH  4 , Thomas MÜLLER-SACHERER  4 and Gabriela BERLAKOVICH  5 1) Wilhelminenspital der Stadt Wien, Urology, Vienna, AUSTRIA - 2) AKH Vienna, Pediatric Surgery, Vienna, AUSTRIA - 3) Medical University of Vienna, Vienna, AUSTRIA - 4) AKH Vienna, Pediatric Nephrology and Gastroenterology, Vienna, AUSTRIA - 5) AKH Vienna, Surgery, Vienna, AUSTRIA PURPOSE Posterior urethral valves (PUV) cause congenital lower urinary tract obstruction and in 30–50 % leads to ESRD. There is conflicting data on outcome of renal transplantation (RT) in PUV. In this study we sought to determine, whether there is a difference in the outcome of RT in PUV compared to control group (NU). MATERIAL AND METHODS In this retrospective long-term study we analyzed possible factors that influence graft function and graft survival. Between 1995 and 2016 there were 149 RT. There were 27 PUV patients, who received 29 grafts. 30 control group patients received 31 renal grafts due to NU diagnosis. RESULTS There was no statistically significant disparity in graft function and estimated graft survival. Graft failure occurred in 23.1 % of the PUV patients and 34.5 % patients in the NU group. In regression analysis only age at transplantation and donor age had an impact on the renal function. There was a higher incidence of UTI in the PUV group. Bladder dysfunction did not play a major role in outcome. Vesicostomy was favorable to other forms of pretransplant intervention in regards of graft function. CONCLUSIONS RT in PUV patients is successful with the same outcome as in NU patients. Good long-term out- comes can be expected. Bladder dysfunction does not have a major impact on graft function and survival in our cohort. It seems that the type of pre-transplant surgical procedures may influence outcome and we recommend vesicostomy.