ESPU Congress 2018 - Abstract Book

129 11–14 APRIL, 2018, HELSINKI, FINLAND 13:33–13:36 S16-2 (PP) OUTCOME OF KIDNEY TRANSPLANTATION FROM YOUNG PEDIATRIC DONORS (AGED LESS THAN 6 YEARS) TO YOUNG SIZE-MATCHED RECIPIENTS Romy GANDER  1 , Marino ASENSIO  1 , José Andrés MOLINO  2 , Gloria Fatou ROYO  1 , Montserrat AGUILERA PUJABET  3 , Luis Enrique LARA  4 , Gema ARICETA  4 and Manuel LOPEZ  3 1) University Hospital Vall d'Hebron. Barcelona, Pediatric Surgery. Pediatric Urology and Renal Transplant Unit, Barcelona, SPAIN - 2) University Hospital Vall d'Hebron. Barcelona, Pediatric Surgery. Renal Transplant Unit, Barcelona, SPAIN - 3) University Hospital Vall d'Hebron Barcelona, Pediatric Surgery, Barcelona, SPAIN - 4) University Hospital Vall d'Hebron Barcelona, Pediatric nephrology, Barcelona, SPAIN PURPOSE Pediatric donation is underutilized due to presumed increased risk of vascular thrombosis (VT) and graft loss. Using young pediatric donors (YPD) for young pediatric recipients (YPR) is suggested to be even at greater risk and therefore precluded in many centers. The aim of this study was to analize the outcome of Kidney Transplantation (KT) from YPD to age-matched YPR. MATERIAL AND METHODS Retrospective study of 118 pediatric KT performed between January 2007–July 2017. We identified KT with YPD (considered as those aged <6 years) and age-matched YPR. Data were collected regarding donor and recipients characteristics, surgical and urological complications, graft loss and outcomes. RESULTS Forty cases were identified (33.89 %). Mean recipient and donor age was 2.9 years (SD:1.68) and 2.24 years (SD: 1.5), respectively. Mean recipient and donor weight was 12.7 kg (SD: 4.1) and 13.7 kg (SD:4.15), respectively. Thirty (75 %) recipients weighed <15 kg. The most frequent primary renal disease was congenital nephrotic syndrome (13). Nine (22.5 %) had received a previous KT. Three received a combined liver-KT. Eight (20 %) were at high immunological risk and 19 (47.5 %) at high thrombotic risk. All allografts were implanted extraperitoneally. Major complications requiring reintervention ap- peared in 7 (17.5 %): 3 VT, 3 bleedings and 1 ureteral necrosis. Remarkably, only 1 surgical com- plication (VT) was related to graft loss. Regarding to long-term urological complications, 4 (10 %) developed VUR to the graft (all had underlying uropathy). As a whole 8 patients lost their graft (20 %). Actuarial graft survival at 1,5–10 years was 83 %–78 %–78 %, respectively. Mean follow-up was 49 months (SD:38.8). CONCLUSIONS We suggest that KT using YPD for age-match YPR yields good results, even in high-risk patients and is associated with good graft survival. In our series, surgical complications were rarely related to graft loss.