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187

11–14 APRIL, 2018, HELSINKI, FINLAND

S26: AUGMENTATION / DIVERSION

Moderators: Raimund Stein (Germany), Mark Cain (USA)

ESPU Meeting on Saturday 14, April 2018, 12:48–13:36

12:48–12:53

S26-1 (LO)

DEMUCOSALIZED SIGMOID BLADDER AUGMENTATION

AND THE REDUCTION OF MUCUS: A COMPARATIVE

INTERNATIONAL MULTICENTRIC PROSPECTIVE STUDY

Ricardo ZUBIETA 

1

, Juan Pablo CORBETA 

2

, Pedro Jose LOPEZ 

1

, Francisco REED 

1

,

Francisca YANKOVIC 

1

, Alejandra RIOS 

1

, Juan Carlos LOPEZ 

2

and Nelly LETELIER 

1

1) Hospital exequiel Gonzalez Cortes & Universidad de Chile, Paediatric Urology, Santiago De Chile, CHILE -

2) HOSPITAL GARRAHAN, Paediatric Urology, Buenos Aires, ARGENTINA

PURPOSE

For the last 25 years our center have been performing demucosalized sigmoid enterocistoplasty to

our patients. It seems that this technique offers a better outcome because it might be is associated

with less mucus production avoiding its associated complications. The aim of this study was to

compare mucus production after enterocistoplasty with or without removing mucosa in two groups

of patients.

MATERIAL AND METHODS

With ethical committee approval a comparative prospective study of mucus production in two

different groups of patients following an enterocistoplasty was done. All patients had more than

5 years follow-up. Patients presenting with recurrent urinary tract infection were excluded. Group

"A" included patients with ileocistoplasty and non-demucosalized colon and group "B" patients with

demucosalized sigmoid. First morning urine was taken through urethral catheterization or through

urinary continent derivation. In a wintrobe tube, 10 cc of urine were centrifuged at 2500 rpm for

10 minutes. A blinded microscopic analysis with mucus quantification and statistic analysis between

both groups was made.

RESULTS

Seventy patients were included in this study (52 Group A and 18 Group B). Mucus amount for

Group B was statistically lower (p=0.0061; CI 95 %). It is also highlighted, that all patients treated in

Group A need daily bladder washout compared with patients from Group B whom did not performed

bladder washouts.

CONCLUSIONS

A lower mucus amount and production in patients with demucosalized sigmoid enterocistoplasty

was confirmed. This technique might offer a better long-term outcome, reducing mucus-related

complications; i.e. stones formation and UTI.