ESPU Congress 2018 - Abstract Book

128

CONGRESS OF THE ESPU

S16: RENAL TRANSPLANTATION

Moderators: Wouter Feitz (Netherlands), Simona Gerocarni-Nappo (Italy)

ESPU Meeting on Friday 13, April 2018, 13:30–13:54

13:30–13:33

S16-1 (PP)

LONG-TERM OUTCOME OF PEDIATRIC RENAL

TRANSPLANT IN BOYS WITH POSTERIOR URETHRAL

VALVES (PUV)

Doris HEBENSTREIT

, Alexander SPRINGER

, Karin HEBENSTREIT

, Dagmar

CSAICSICH

, Thomas MÜLLER-SACHERER

and Gabriela BERLAKOVICH

1) Wilhelminenspital der Stadt Wien, Urology, Vienna, AUSTRIA - 2) AKH Vienna, Pediatric Surgery, Vienna, AUSTRIA -

3) Medical University of Vienna, Vienna, AUSTRIA - 4) AKH Vienna, Pediatric Nephrology and Gastroenterology, Vienna,

AUSTRIA - 5) AKH Vienna, Surgery, Vienna, AUSTRIA

PURPOSE

Posterior urethral valves (PUV) cause congenital lower urinary tract obstruction and in 30–50 %

leads to ESRD. There is conflicting data on outcome of renal transplantation (RT) in PUV. In this

study we sought to determine, whether there is a difference in the outcome of RT in PUV compared

to control group (NU).

MATERIAL AND METHODS

In this retrospective long-term study we analyzed possible factors that influence graft function

and graft survival. Between 1995 and 2016 there were 149 RT. There were 27 PUV patients, who

received 29 grafts. 30 control group patients received 31 renal grafts due to NU diagnosis.

RESULTS

There was no statistically significant disparity in graft function and estimated graft survival. Graft

failure occurred in 23.1 % of the PUV patients and 34.5 % patients in the NU group. In regression

analysis only age at transplantation and donor age had an impact on the renal function. There

was a higher incidence of UTI in the PUV group. Bladder dysfunction did not play a major role in

outcome. Vesicostomy was favorable to other forms of pretransplant intervention in regards of graft

function.

CONCLUSIONS

RT in PUV patients is successful with the same outcome as in NU patients. Good long-term out-

comes can be expected. Bladder dysfunction does not have a major impact on graft function and

survival in our cohort. It seems that the type of pre-transplant surgical procedures may influence

outcome and we recommend vesicostomy.