Parallel Meeting on Wednesday 17, June 2026, 16:55 - 17:55
16:55 - 16:58
S07-1 (CP)
Rennen HARAMATY 1, Irene CHOI 1, Leeyan NASRALLAH 1, Kali MESDJIAN 1, Jennika FINUP 1, Madeleine RAPISARDA 2, Javier SANTIAGO 2, Vinaya BHATIA 1, Walid FARHAT 1, Marcela AMBROGI 2 and Kristin EBERT 1
1) University of Wisconsin School of Medicine and Public Health, Division of Pediatric Urology, Department of Urology, Madison, USA - 2) University of Wisconsin School of Medicine and Public Health, Department of Urology, Madison, USA
PURPOSE
Transitional urology focuses on lifelong sexual and reproductive health in patients with congenital urologic disease. While sexual dysfunction (SD) is well documented in neurogenic bladder (NB), less is known about adolescents and young adults (AYA) with non-neurogenic congenital urologic conditions (NNCUC). This study compares sexual function and psychosocial factors between these groups to identify predictors of sexual health readiness during transition.
MATERIAL AND METHODS
We prospectively collected data for patients seen in our Transitional Urology Clinic between August 2024 and August 2025. All were offered standardized sexual health surveys (SHIM for men, FSFI-6 for women) and a transition readiness assessment (TRAQ); patients with completed surveys were included. Data on age, sex, diagnosis, living situation, guardianship, and sexual activity/interest were also collected. SD was defined as SHIM < 17 (men) or FSFI-6 < 19 (women). Analyses were performed using chi-square and t-tests in SPSS.
RESULTS
Of 50 patients (25 male, 50%), 37 (18 male, 48%) completed surveys; 29 (78%) had NB. Sexually active patients had lower SD rates than inactive patients (25% vs 96%, p < 0.001). Living independently (62% vs 92%, p = 0.072) and self-guardianship (71% vs 100%, p = 0.070) were associated with lower SD rates. Patients with SD had lower mean TRAQ scores than those without (76 vs 96, p = 0.012). NB patients were less likely to be sexually active (13% vs 50%, p = 0.066), though interest in sexual activity/fertility was similar (24% vs 38%, p = 0.57). SD was highly prevalent in both NB (86%) and NNCUC (63%) groups (p = 0.16).
CONCLUSIONS
Sexual dysfunction is common among AYAs with congenital urologic conditions, regardless of neurogenic status. Functional dependence and low transition readiness correlate with poorer sexual health, highlighting the need for structured sexual health assessment and counseling in transitional urology to promote autonomy and adult independence.
16:58 - 17:01
S07-2 (CP)
Eman CHAUDHRI 1, Johana PAEZ CORTES 1, Claudio NOME 2, Sonia PEREZ-BERTOLEZ 3, Jose Luis FADIL 4, Jenny ARBOLEDA 5, Chelsy LASSO BETANCOR 6, Paz BUSTAMANTE 7, Alejandro ACQUISGRANA 8, Juan MOLDES 1, Pedro-Jose LOPEZ 1 and Francisco REED 9
1) University Hospitals Cleveland Medical Center/Case Western Reserve University, Urology, Cleveland, USA - 2) Clinica Mayor; Hospital de Salud Intercultural Nueva Imperial, Pediatric Surgery, Temuco, CHILE - 3) Sant Joan de Deu Barcelona Children's Hospital, Pediatric Urology, Barcelona, SPAIN - 4) Sanatorio de Niños, Pediatric Urology, Rosario, ARGENTINA - 5) Hospital Metropolitano, Pediatric Urology, Quito, ECUADOR - 6) Hospital Universitario de Canarias, Pediatric Surgery, Tenerife, SPAIN - 7) Hospital Provincial de Ovalle, Pediatric Surgery, Ovalle, CHILE - 8) Hospital Pediátrico Avelino Castelán, Pediatric Urology, Resistencia, ARGENTINA - 9) Hospital Exequiel Gonzalez Cortés, Urology, San Miguel, CHILE
PURPOSE
Genitourinary (GU) polyps in children are rare lesions that may arise anywhere along the urinary tract, presenting asymptomatically or with symptoms such as obstruction or bleeding. Existing literature consists mostly of isolated case reports and small single-center series, limiting understanding of their clinical behavior, histologic spectrum, and outcomes. We aimed to describe the demographics, presentation, localization, management, and follow-up of pediatric GU polyps in a global multicenter cohort.
MATERIAL AND METHODS
A retrospective descriptive study was conducted of children <18 years with histologically confirmed GU polyps. Cases were contributed by members of the Iberoamerican Society of Pediatric Urology (SIUP) and the European Society for Pediatric Urology (ESPU). Patients ≥18 years or with insufficient data were excluded. Demographic, clinical, imaging, operative procedures, anatomic, histopathologic, and follow-up variables were analyzed descriptively.
RESULTS
Between 2007 and 2025, 26 children with 27 GU polyps were identified from 14 centers across 7 countries. Eighteen (69%) were male. Mean age at surgery was 6.8 years (range 7 days-17 years). The majority of polyp locations included the urethra (40.7%) and bladder (40.7%) (Table 1). Main presenting manifestations included hematuria (37%) and obstruction/urinary retention (26%). Ultrasound was obtained in 22 children, with 27% showing no specific findings; voiding cystourethrogram was performed in 6 patients, all with polyp visualization. Initial management included endoscopic or transurethral resection/fulguration (n=20), open resection (n=5), and robotic reconstruction (n=2). Histopathology demonstrated fibro-epithelial polyps (48%), non-specified polyps (30%), and papilloma with malignant features in 6 cases (22%) (Table 1). Follow-up was available for 20 children (mean 2.9 years; range 1-10 years), and only 1 recurrence occurred after 1 year.
Table 1:
| Results | Total Polyps: 27 | |
| Location of Polyp | Urethra Bladder Ureter Ureteropelvic junction Renal calyx |
11 11 3 1 1 |
| Presentation | Hematuria Obstruction Prolapse Pain Antenatal diagnosis Incidental |
10 7 4 3 2 1 |
| Histopathology | Fibroepithelial polyp Non-specified polyp Papilloma (malignant) |
14 7 6 |
CONCLUSIONS
This global multicenter series demonstrates anatomic diversity, varied presentation, and the predominantly benign nature of rare conditions such as pediatric GU polyps. Endoscopic resection is the most common (67%) and usually definitive therapy, with low recurrence and favorable long-term outcomes. Resection and histopathology are mandatory, as 22% of lesions in our cohort exhibited malignant characteristics and 1 recurrence. This warrants a better definition of their clinical trajectory and ongoing structured long-term follow-up for these patients.
17:01 - 17:04
S07-3 (CP)
Roberto LOPES, Gabriela WOJCIECHOWSKI, Ana PIMENTA, Rodrigo NASCIMENTO, Jessica PEREIRA, Afonso BENTO, Alessandro TAVARES, Sabrina REIS and Francisco DÉNES
University of São Paulo Medical School, Division of Urology, Department of Surgery, São Paulo, BRAZIL
PURPOSE
Prune Belly Syndrome (PBS) is a rare congenital condition characterized by abdominal wall deficiency, urinary tract malformations, and bilateral cryptorchidism. Optimal management remains challenging and requires individualized, multidisciplinary surgical strategies. This study aimed to report our long-term experience with comprehensive surgical management of PBS in the largest cohort described to date.
MATERIAL AND METHODS
Between 1987 and 2025, 103 children with PBS were evaluated at our institution (according to Woodard’s severity grading: PBS I: 5 pts, PBS II: 84 pts and PBS III: 14 pts). Surgical treatment was individualized and aimed to correct abdominal wall flaccidity, reconstruct the urinary tract, and perform bilateral orchiopexy and circumcision in a single operative stage whenever feasible. Upper urinary tract reconstruction was indicated in the presence of significant pyelo-ureteral dilatation with evidence of urinary stasis and/or vesicoureteral reflux associated with recurrent urinary tract infections. Clinical, functional, and anatomical outcomes were analyzed.
RESULTS
82 patients were submitted to comprehensive surgical management. A total of 73 abdominoplasties, 68 upper urinary tract reconstructions, 76 lower urinary tract reconstructions, 96 bilateral orchiopexies, 97 circumcisions, and 5 urethroplasties were performed. Median age at surgery was 18.1 months, and median follow-up was 14.2 years. Improvement in abdominal appearance and muscle tone was observed in >90% of patients after the primary procedure. Functional stabilization of the upper urinary tract occurred in 90% of children, while progression to renal failure was observed in 10%. Urinary continence was achieved in 85% of patients; persistent incontinence in 15% was most often associated with polyuria. After bilateral orchiopexy, >90% of testes were orthotopic and of normal size.
CONCLUSIONS
Comprehensive surgical management tailored to individual patient needs provides satisfactory long-term outcomes for abdominal wall, urinary tract anatomy and function, urinary continence, and testicular position in children with PBS. This large cohort with extended follow-up supports comprehensive surgery as an effective strategy for the management of Prune Belly Syndrome.
17:04 - 17:07
S07-4 (CP)
Sarah ABDELLAOUI 1, Emanuela GALLO 1, Fabiana CAZZORLA 2, Valeska BIDAULT 1, Anne-Laure SELLIER-LECLERC 3, Frédéric HAMEURY 1, Pauline GASTALDI 4, Delphine DEMEDE 1 and Alice FAURE 4
1) Hôpital Femme Mere Enfant, Hospices Civils de Lyon, Pediatric Urology, Lyon, FRANCE - 2) Université Grenoble Alpes, Service de maladies infectieuse, Grenoble, FRANCE - 3) Hôpital Femme Mere Enfant, Hospices Civils de Lyon, Pediatric Nephrology, Lyon, FRANCE - 4) Hôpital La Timone Enfant, Assistance Publique - Hôpitaux de Marseille (APHM), Pediatric Urology, Marseille, FRANCE
PURPOSE
The choice of uretero-ureterostomy (UU) as primary ureteral anastomosis technique in pediatric kidney transplantation (KT) remains debated. This study aims to compare urological outcomes following Lich-Gregoir (LG) versus UU anastomosis in children undergoing KT for nephrological end-stage renal disease (ESRD) with normal bladder function.
MATERIAL AND METHODS
This retrospective bicentric cohort study included all KT recipients
RESULTS
A total of 146 KT were included: 103 (70.5%) in the LG group and 43 (29.5%) in the UU group. Groups were comparable at baseline except for warm ischemia time, pre-transplant hemodialysis, and JJ stent use. Median [IQR] follow-up was 5.1 [2.3–7.1] years. At least one urological complication occurred in 62 (42.4%) KT, and two in 16 (10.9%), accounting for 78 events. Overall complication rates were similar between LG and UU (39.8% vs 48.8%; p=0.3) and remained comparable after excluding isolated acute pyelonephritis (32.6% vs 45.0%; p=0.2). However, UU was associated with significantly higher rates of urinary fistula (16.3% vs 2.9%; p=0.011) and JJ stent dysfunction (14.0% vs 0%; p<0.001). Vesicoureteral reflux was rare (n=3), all after LG. Among 78 complications, 45 (57.7%) were Clavien–Dindo grade III. Severe events (grade III–V) were more frequent with UU (75.9% vs 49.0%; p=0.004). Graft loss occurred in 10 patients (6.9%), with no difference between techniques.
CONCLUSIONS
In pediatric KT for nephrological ESRD with normal bladder function, LG and UU demonstrated similar overall urological morbidity. However, UU was associated with a significantly higher rate of urinary fistula and severe complications, suggesting that the LG technique may offer a more stable urological safety profile in this setting
Abstract table:Overall urological complications rate
|
|
LG group |
UU group |
p-value |
|
Total of KT, n |
103 |
43 |
NA |
|
Overall complication rate, n (%) |
41 (39.8) |
21 (48.8) |
0.3 |
|
Overall complication rate excluding isolated APN episodes, n (%) |
30 (32.6) |
18 (45.0) |
0.2 |
LG: Lich-Gregoir; UU: Ureteroureterostomy; KT: Kidney transplantation; APN: Acute pyelonephritis; NA: not applicable
17:22 - 17:25
S07-5 (CP)
Ursula TONNHOFER 1, Marie ANDERSSON 2, Anne- Francoise SPINOIT 3, Matthieu PEYCELON 4, Don Andre VINCENTELLI 5, Rosa ROMERO 6, Alexander TURNER 7, Alexander SPRINGER 8, Annabel PAYE JAOUEN 9 and Valeska BIDAULT-JOURDAINNE 10
1) Medical University Vienna, Paediatric Surgery, Vienna, AUSTRIA - 2) Queen Silvia Children's Hospital, Sahlgrenska Academy at the University of Gothenburg, Pediatric Surgery, Gothenburg, SWEDEN - 3) Ghent University Hospital, Department of Urology, Division of Paediatric Urology,, Ghent, BELGIUM - 4) National Reference Center for Rare Urinary Tract Malformations (CRMR MARVU), ERN eUROGEN accredited center, Robert-Debré UniversityHospital, APHP, GHU North, Université Paris Cité, Department of Pediatric Surgery and Urology, Paris, FRANCE - 5) Centre Hospitalo-Universitaire de Saint Étienne, Pediatric Surgery, Saint Priest En Jarez, FRANCE - 6) Hospital Universitario Virgen del Rocío, Pediatric Urology Unit, Seville, SPAIN - 7) Leeds Children's Hospital, Department of Paediatric Urology, Leeds, UNITED KINGDOM - 8) Medical University Vienna, Pediatric Surgery, Vienna, AUSTRIA - 9) National Reference Center for Rare Urinary Tract Malformations (CRMR MARVU), ERN eUROGEN accredited center, Robert-Debré University, Hospital, APHP, GHU North, Université Paris Cité,,, Department of Pediatric Surgery and Urology,, Paris, FRANCE - 10) HFME, Hospices Civils de Lyon, CRMR DEVGEN, CRMR MARVU, Inserm U1208 SBRI, Université Claude Bernard Lyon 1, Pediatric urovisceral, thoracique and transplantation departmen, Lyon, FRANCE
PURPOSE
Zinner Syndrom is a genito- urinary malformation of the mesonephric duct in 2,2/ 100.000 male live births. First described in 1914, it is associated with renal agenesis or multicsystic renal hypoplasia, cystic dilatation of the seminal vesicle (SVC), ipsilateral obstructed ejaculatory duct and ectopic ureteral pathology. Clinical presentation can be variable and age-dependent: symptomless, recurrent UTI, epididymitis or infertility. Prenatal diagnosis of renal agenesis is common.
MATERIAL AND METHODS
Our multicenter retrospective study includes 3 European countries and 5 different departments. 39 patients were included. Mean age at diagnosis was 3,7 years (0-17a), diagnostic tools (ultrasound, MRI and CT) were analyzed. Different interventions are described. All patients benefit a yearly nephrological follow up due to solitary kidney.
Statistical analysis: descriptive
RESULTS
Treatment options encompass observation (11 patients) with regular clinical and ultrasound follow-up, antibiotic prophylaxis, endoscopic treatment with trans-urethral puncture, incision or unroofing of the cyst for decompression or minimal invasive uretero-nephrectomy and SVC excision. In our series 11 patients were treated conservatively with surveillance. 5 had only cystoscopy, one was treated with incision, 22 had nephroureterectomy of which 3 had additional excision of the SVC. Four required secondary surgery of SVC because of symptoms in adulthood (pyelonephritis, orchitis and epididymitis or lower urinary tract symptoms). Follow up period is 7 years (range 0,2- 18,4 a).
CONCLUSIONS
So far, no guidelines exist in pediatrics for this rare male urogenital malformation. It may be underreported in literature. Endoscopic or minimally invasive surgery might be curative for symptomatic patients but management is not standardized. Long term follow -up will be
needed for prepubertal patients. The diversity in morphology and clinical findings makes diagnosis and treatment challenging. Although Zinner Syndrome is early diagnosed, fertility problems may occur later.
17:25 - 17:28
S07-6 (CP)
Saniya ANSARI 1, Christopher PARRY 1 and Harriet CORBETT 2
1) Alder Hey Children's NHS Foundation Trust, Liverpool, UNITED KINGDOM - 2) Alder Hey Children's NHS Foundation Trust, Regional Department of Urology, Liverpool, UNITED KINGDOM
PURPOSE
Urinary tract infections (UTIs) are a common cause of illness in children under 5 years. Congenital abnormalities of the kidneys and urinary tract (CAKUT) and continuous antimicrobial prophylaxis (CAP) may influence causative organisms and antimicrobial resistance patterns. This study examined clinical management and microbiological findings in children under 5 years presenting with UTIs across six hospitals in North-West England and North Wales.
MATERIAL AND METHODS
A prospective observational study with data collected between April 2024 and March 2025. Eligible children under 5 years with positive urine cultures and available colony counts were included. Data collected included demographics, CAKUT status, CAP use, organism type, antibiotic treatment, and resistance patterns. Statistical comparisons were performed using χ², Fisher’s exact test, and Mann–Whitney tests, with statistical significance set at p ≤ 0.05.
RESULTS
Of 137 patients, 115 met inclusion criteria (58% female, median age 8.5 months). The commonest symptoms reported were fever (80/115, 68%), vomiting (45/115, 36%) and feed refusal (45/115, 36%). Escherichia coli was the most common organism cultured (73/115, 64%). CAKUT was present in 17% (n=20 of whom 10 had VUR) and was significantly associated with infection by non-E. coli organisms (p=0.003) and also with CAP use pre- and post-UTI (p<0.0001). Growth of an atypical,non-E. coliorganism fell just outside the significance threshold of p= 0.05 when tested for association with the use of CAP (p= 0.051).
The most common antibiotic used to treat the UTI was cefalexin (62/115, 54%); 84 (73%) patients grew organisms susceptible to the initial treatment. All thirteen (11%) patients treated initially with an antibiotic to which the cultured organism was resistant resided in Cheshire and Merseyside. There was no significant difference in susceptibility to initial antibiotic treatment between CAKUT and non-CAKUT groups, or between CAP and non-CAP groups. Regional prescribing patterns differed according to local guidelines.
CONCLUSIONS
Children with CAKUT were more likely to develop atypical UTIs caused by non-E. coli organisms, though presence of CAKUT and/or CAP was not adversely linked to susceptibility to initial antibiotic choice in this cohort. Local antimicrobial resistance patterns and patient comorbidities should be considered when developing treatment guidelines.
17:28 - 17:31
S07-7 (CP)
Athanasios TYRASKIS 1, Zeni HAVELIWALA 2, Suzannah WOODHOUSE 1, Sonia BASSON 2, Stavros LOUKOGEORGAKIS 2, Simon BLACKBURN 2, Joseph CURRY 2, Divyesh DESAI 2, Neetu KUMAR 1 and Abraham CHERIAN 1
1) Great Ormond Street Hospital, Paediatric Urology, London, UNITED KINGDOM - 2) Great Ormond Street Hospital, Specialist Paediatric and Neonatal Surgery, London, UNITED KINGDOM
INTRODUCTION
Cloacal malformations are associated with high rates of renal anomalies and chronic kidney disease. Evidence to support strategies on renal function preservation is sparse. We aim to identify factors associated with a decline in renal function in patients born with cloacal malformations.
METHODS
A single-centre case review was performed, patients with a cloacal malformation were considered for inclusion, and those referred after reconstruction were excluded. Anatomical, operative, laboratory, and radiological information were gathered.
The primary outcome was requiring renal replacement therapy or transplantation(RTT). Secondary outcomes were worsening of renal function, presence of renal scars on scintigraphy, and febrile urinary tract infections(UTIs). Worsening of renal function was defined as an increase in the stage of chronic kidney disease(CKD) or acquiring new cortical scars on scintigraphy. Glomerular filtration rate(GFR) was estimated using the bedside Swartz formula. A long common channel was defined as 3cm or longer. Data are displayed as median and inter-quartile range(IQR), categorical data are analysed using a two-tailed Fisher’s Exact test, and a P value of <0.05 was considered significant.
RESULTS
82 patients referred at birth or for reconstruction were included and 3(4%) were lost to follow-up. Median age at referral was 1 month(IQR birth-9 months) and latest creatine was taken at a median 4 years(IQR 1.9 years-8.9 years). Renal transplantation or RTT was needed in 5(6%) of which 4 were in CKD stage 5 on initial evaluation and 1 in CKD stage 4. 58(70%) started with an eGFR ≥90ml/min/1.73m² and 54(93%) retained this.
17(21%) patients showed a decline in renal function. 3(4%) reached an eGFR<30ml/min/1.73m², 1(1%) of 30-59ml/min/1.73 m², 6(7%) of 60-89ml/min/1.73 m², and 7 (9%) acquired new cortical scars with an eGFR ≥90ml/min/1.73m².
The presence of vesicoureteric reflux (P=0.0056) and a long common channel (P=0.047) was associated with a decline of renal function. Two normal kidneys and collecting systems on initial evaluation was associated with stable renal function (P=0.009); of which 1/20 (5%) developed a febrile UTIs, and none had a decline of renal function.
Factors not associated with decline in renal function were the presence of hydrocolpos(P=0.42), spinal cord anomalies(P=1.0), grade 4/5 vesicoureteric reflux (P=0.35), febrile UTIs(P=0.23), unclassified cloaca(P=0.75), and cortical scars on initial scintigraphy(P=0.08).
|
CKD Stage |
eGFR (mL/min/1.73 m²) |
Patients on initial evaluation (n) |
|
Stage 1 |
≥90 |
58 |
|
Stage 2 |
60-89 |
10 |
|
Stage 3 |
30-59 |
6 |
|
Stage 4 |
15-29 |
3 |
|
Stage 5 |
<15 |
4 |
|
Missing labs |
|
1 |
Table 1. Table showing the CDK category of patients on initial evaluation
CONCLUSIONS
Long common channel and VUR were associated with a decline in renal function, whereas the presence of two normal kidneys and collecting systems was a protective association.
17:31 - 17:34
S07-8 (CP)
Jenna HOUARI 1, Alice FAURE 2, Alexis ARNAUD 3, Julien ROD 4, Jean Baptiste MARRET 4, Pauline LOPEZ 5, Nathalie BOTTO 6 and Quentin BALLOUHEY 7
1) Limoges University Hospital, Limoges, FRANCE - 2) Marseille Universiy Center, Department of Pediatric Surgery, Marseille, FRANCE - 3) CHU de Rennes, Rennes, Service de Chirurgie Viscérale Pédiatrique, Rennes, FRANCE - 4) Caen University Hospital Center, Service de Chirurgie Viscérale et Urologie Pédiatrique,, Caen, FRANCE - 5) Limoges University Hospital Centre, Limoges, FRANCE - 6) Hôpital Necker-Enfants Malades, APHP, Paris, France Université Paris Cité, Paris, France, Service de Chirurgie Viscérale, Urologie et Transplantation Pédiatrique,, Paris, FRANCE - 7) Limoges University Hospital Centre, Department of Pediatric Surgery, Limoges, FRANCE
PURPOSE
Prepubic sinus (PPS) is a rare congenital entity presenting as an abnormal midline opening in the prepubic area, extending as a fibrous remnant to the bladder anterior wall. Its embryological origin remains unclear and very few cases have been reported. Our aim was to collect our multicenter experience in order to report current management.
MATERIAL AND METHODS
A systematic retrospective study was conducted across seven University Pediatric Urological Reference centers over the last 10 years. Demographic, radiological, surgical and histological data were collected in order to describe diagnostic and management process in light of existing literature.
RESULTS
From 2014 to 2024, seven patients were identified (5 males, 2 females) aged 0-8 years at diagnostic in five centers. Associated anomalies were found in two patients (cardiac malformation; meatal fossa of the glans). Five children were symptomatic (pain=1, intermittent purulent discharge=5). Clinical examination suggested a congenital sinus in all cases. Ultrasonography was performed for all patients and raised suspicion of urinary tract involvement. Fistulography (n= 5) showed no urinary tract connection. Complete surgical resection was achieved for the five symptomatic cases. Intra-operative cystoscopy confirmed the absence of connection to the urinary tract. Histology showed transitional and squamous epithelium supporting a potential shared origin between PPS and lower urinary tract (LUT). Conservative management was conducted for the two asymptomatic cases without occurrence of symptoms after a mean follow-up of 39 (12-55) months.
Since its first report nearly 40 years ago, less than 90 cases of PPS have been reported. The large majority have no connection (5%) with LUT and no associated abnormalities (3%). One case of laparoscopic extra peritoneal approach was reported. This PPS series represent the largest ever described. MRI, cystoscopy or per operative methylene blue opacification are good options to explore potential LUT connection.
CONCLUSIONS
PPS appears to be an isolated and benign abnormality of the middle line, potentially sharing common origin with LUT development. Surgical excision is effective for symptomatic cases, while conservative management is appropriate in asymptomatic children.