ESPU Congress 2018 - Abstract Book

98 29 th CONGRESS OF THE ESPU 16:25–16:28 S11-6 (PP) ★ NON-MODIFIABLE PREDICTIVE FACTORS FOR COMPLICATIONS IN THE DUTCH HYPOSPADIAS STUDY Goedele BECKERS  1 , Fred VAN DER TOORN  2 , Keetje DE MOOIJ  3 , Robert DE GIER  4 , Rien NIJMAN  5 , Piet CALLEWAERT  6 , Martijn STEFFENS  7 , Eric VAN DER HORST  8 , Piet HOEBEKE  9 , Frank FROELING  10 , Mark WILDHAGEN  11 and Katja P. WOLFFENBUTTEL  12 1) VU University Medical Center, Paediatric Urology, Amsterdam, NETHERLANDS - 2) Sophia's Children Hospital, Pediatric Urology, Rotterdam, NETHERLANDS - 3) University Children's Hospital UMC, Pediatric Renal Center, Utrecht, NETHERLANDS - 4) Radboud University Medical Center, Pediatric Urology, Nijmegen, NETHERLANDS - 5) University Medical Center Groningen, Pediatric Urology, Groningen, NETHERLANDS - 6) Maastricht University Medical Center, Pediatric Urology, Maastricht, NETHERLANDS - 7) Isala Hospital Zwolle, Pediatric urology, Zwolle, NETHERLANDS - 8) VU University Medical Center, Pediatric Urology, Amsterdam, NETHERLANDS - 9) University Hospital Gent, Pediatric Urology, Gent, BELGIUM - 10) Haga Hospital The Hague, Pediatric Urology, Den Haag, NETHERLANDS - 11) Erasmus Medical Center, Unit of Trials and Research Coordination, Rotterdam, NETHERLANDS - 12) Sophia's Children Hospital, Pediatric Urology, Rotterdam, NETHERLANDS PURPOSE The position of the meatus and of the division of the corpus spongiosum (DCS) are considered predictive factors for the outcome of hypospadias surgery. We determine the odds of non-modifiable factors registered in the Dutch Hypospadias Study database (DHyS) for postoperative complications. MATERIAL AND METHODS The DHyS contains prospective data of 1233 evaluable patients. The relation between pre- and dysmaturity, meatal position, position of DCS, preoperative penile length, penile curvature (more than 30 degrees after deglovement) and complications 6 months after first correction were investi- gated with logistic regression. Categorical variables were coded from less to more severe. RESULTS 46(5.4 %) children were born pre- and/or dysmaturely: median age at birth gestational week 35(IQR 32–37), birth weight 1862grams(IQR 1200–2500). Birth weight of all other children was not registered. For all cases, meatal position was 291 glanular, 757 coronal/distal shaft, 83 midschaft, 56 proximal and 46 penoscrotal. The position of DCS was: 681 distal shaft, 392 midshaft, and 160 proximal shaft. Preoperative penile length was 43 mm(IQR 35–50). Penile curvature was seen in 894 cases. 185 children had no urethraplasty. 250 children(20 %) had a postoperative complication. Univariate and multivariate analysis of significant outcome variables are shown. Pre-or dysmaturity and penile length at operation were not significant for outcome(p=0.538 and p=0.581 resp). Univariate analysis Multivariate analysis Odds CI Odds CI Meatal position 1.652 1.537–1.775 1.415 1.281–1.562 Position division corpus spongiosum 1.835 1.667–2.020 1.346 1.180–1.534 Penile curvature 1.587 1.363–1.848 0.996 0.910–1.090 CONCLUSIONS Meatal position and position of DCS are the only contributing non-modifiable predictive factors for complications after hypospadias surgery. Pre- or dysmaturity, penile length and penile curvature did not influence outcome significantly.