ESPU Congress 2018 - Abstract Book

83 11–14 APRIL, 2018, HELSINKI, FINLAND CONCLUSIONS Revision scrototomy is indicated in all cases, when the testicular volume exceeds 2.25 ml, diagnos- tic laparoscopy is an optimal starting procedure for patients with the contralateral testicular volume under 1.04 ml. 14:08–14:11 S9-3 (PP) TUBULAR FERTILITY INDEX (TFI) IN CORRELATION WITH TESTIS POSITION, CONSISTENCY, EPIDIDYMAL ANATOMY AND AGE AT ORCHIDOPEXY IN 237 BOYS WITH CRYPTORCHIDISM Katja P. WOLFFENBUTTEL  1 , Ries KRANSE  2 , Hans J.A. STOOP  3 , Fred VAN DER TOORN  1 , J.W. OOSTERHUIS  3 , Katharina BIERMANN  3 , Jeroen R. SCHEEPE  1 , Joop VAN DEN HOEK  1 and Leendert H.J. LOOIJENGA  3 1) Erasmus MC - Sophia Children's Hospital, Pediatric Urology, Rotterdam, NETHERLANDS - 2) Netherlands Comprehensive Cancer Organisation (IKNL), Rotterdam, NETHERLANDS - 3) Erasmus MC, Pathology, Rotterdam, NETHERLANDS PURPOSE Epididymal anomalies in cryptorchidism are common, especially in proximal positioned testes. Aims of the study were to: 1. classify epididymal anatomy according to a modified scoring system in 8 categories; 2. investigate the percentage of germ cell containing seminiferous tubules, Tubular Fertility Index (TFI), in a testicular biopsy taken during orchidopexy; 3. compare TFI with recorded clinical information on testis position, consistency, epididymal anatomy and age at orchidopexy. MATERIAL AND METHODS Between 2001 and 2017 testicular histology from 237 patients (263 testes) with cryptorchidism was available for review; 60 patients (68 testes) with missing data on clinical variables but with documented TFI and age at surgery were initially excluded. The remaining 177 patients (195 tes- tes), aged between 5 and 244 months (mean 39 months) were investigated. For statistical analysis fractional logistic regression analysis was used. RESULTS Testis position was abdominal in 20 (11 %), internal ring in 54 (27 %), canalicular in 84 (43 %) and external ring in 37 (19 %). Testis consistency was normal in 58 (30 %), soft in 59 (30 %) and inter- mediate in 78 (40 %). Normal epididymal anatomy (category 1 and 2) was seen in only 68 (35 %) testes. The TFI was >60 % in 50 testes (26 %); 30–60 % in 55 (28 %); < 30 % in 65 (33 %) and 0 (SCO) in 25 (13 %). Fractional logistic regression analysis showed that age at orchidopexy was the only clinical parameter that significantly predicted the TFI (p 0.00). The obtained model for TFI was validated in the initially excluded 68 testes because of incomplete data, but documented TFI and age at surgery. CONCLUSIONS Exclusively age at orchidopexy correlated significantly with TFI. TFI decrease with age at surgery suggests that current guidelines for timing of orchidopexy in boys with undescended testes (be- tween 6 and 18 months) should be tightened to the age of 6 months or soon afterwards. 14:11–14:20 Discussion