Upcoming Events Calendar

For more information about the meeting, including the program and registration, please visit: https://cryptorchidism.org and click on “Get Tickets.” in order to register your place.

Programme:

Day 1:

9:00-9:05 FarukHadziselimovic(Liestal):Welcome address

Molecular biology 1.
Chair: Mizuno Kentaro (Nagoya)
9:05-9:30 Vincent Prevot (Lille): Molecular biology of the mini-puberty, LH-RH and cognition
9:30-9:55 Rodolfo Ray (Buenos Aires):The physiology of the transient postnatal activation of the hypothalamic-pituitary-testicular axis
9:55-10:20 Antoine Peters (Basel): Epigenetic gene regulation in male germ cell development.
10:20-10:45 Birgit Stallmeyer (Münster): Impact of disturbed piRNA biogenesis on transposon de-repression and male infertility

10:45-11:15 Coffee break

Molecular biology 2.
Chair: Gilvydas Verkauskas (Vilnius)
11:15-11:40 Kentaro Mizuno (Nagoya):Biological effects on early-stage spermatogenesis in cryptorchidism
11:40-12:05 Jorma Toppari (Turku): Puberty in boys with a history of cryptorchidism
12:05-12:30 Shosei Yoshida (Okazaki): Roles of temperature and retinoic acid in the spermatogenesis defect associated with cryptorchidism
12:30-12:55 Christian De Geyter (Basel): Altered DNA methylation in estrogen-responsive repetitive sequences of spermatozoa of infertile men with shortened anogenital distance

13:00-14:00 Lunch

Pathophysiology
Chair: Rodolfo Ray(Buenos Aires)
14:00-14:25 Gilvydas Verkauskas (Vilnius):Hypothalamus-pituitary-gonadal axis in cryptorchid boys
14:25-14:50 Darius Dasevicius (Vilnius):Histopathology of cryptorchid tests.
14:50-15:15 Dina Cortes (Copenhagen): Negative effect of hormonal treatment on prepubertal testis
15:15-15:40 Jörgen Thorup (Copenhagen): Testis tissue cryopreservation may be considered for boys with cryptorchidism.
15:40-16:05 Claude Kollin (Stockholm): A prospective randomized study from birth to puberty on testicular volume after orchidopexy

Day 2:

Treatment
Chair: Guy Bogaert (Leuven)
9:00-9:25 Bica Domingos (Rio de Janeiro): Buserelin-treatment; three-arm placebo-controlled study.
9:25-9:50 Dimitrios Papadimitriou (Athens): Replacement of male mini-puberty
9:50-10:15 Filippo Menchini Fabris (Pisa): Long term follow-up of cryptorchid patients following hormonal or hormonal/surgical, surgical or no treatment
10:15-10:40 Faruk Hadziselimovic(Liestal): Molecular evidence supports hormonal treatment

11:10-11:35 Luciano Favorito (Rio de Janeiro): The role of gubernaculum in testicular migration - translational aspects applied to undescended tests

Coffee break 11.35-11.55

11:55-13:30 Round Table Discussion & Videoconferencing to address specific topics and recent advancements and questions by the audience.

Moderators: Guy Bogaert(Leuven)& Gianantonio Manzoni(Milano)

Topics: (5-10 minutes interdiction)

• Pitfalls in cryptorchidism diagnosis. Dragana Zivkovic(Novi Sad)
• Understanding the causes of cryptorchid male infertility - doestemperature play a role?Faruk Hadziselimovic(Liestal)
• Advantages and disadvantages of early orchidopexy. Zacharias Zachariou(Nicosia)
• Benefits and drawbacks of hormonal treatment/orchidopexy). Guy Bogaert(Leuven)
• Is unilateral cryptorchidism an endocrinopathy? Gilvydas Verkauskas(Vilnius)
• Is the current guidance for the clinical management of cryptorchidism up-to-date and based on the latest research findings? BeataVincel(Vilnius)
• GnRH and cognitive development Vincent Prevot(Lille):

Closing Session